Isotopically Labeled Compounds
Medchemexpress LLC Bisphenol A-d8 | 92739-58-7 | 99.3% | 236.34 | 1 MG
Bisphenol A-d8 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. It is classified as a reproductive, developmental, and systemic toxicant, often considered an endocrine-disrupting compound (EDC). Bisphenol A is linked to various health issues including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductive disorders.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs.
Sigma Aldrich Fine Chemicals Biosciences Dimethyl sulfoxide-d6 99.9 atom % D, contains 0.03 % (v/v) TMS | 2206-27-1 | MFCD00002090 | 10X0.6ML
Dimethyl sulfoxide-d6 99.9 atom % D, contains 0.03 % (v/v) TMS | Purity: 99% (CP) | Mol Wt: 84.17 | 2206-27-1 | MFCD00002090 | 10X0.6ML
Medchemexpress LLC Gilteritinib-d8 | 2377109-74-3 | 98.0% | 560.76 | C29H36D8N8O3 | 1MG
Gilteritinib-d8 is the deuterium-labeled internal standard of gilteritinib (ASP2215), supplied as a solid analytical standard for research and quantitative mass spectrometry applications. It is intended for use in method development, ADME studies, and bioanalytical quantitation where an isotopically labeled reference is required.
- Deuterium-labeled internal standard for accurate mass spectrometry quantitation.
- High purity to minimize analytical interference.
- Molecular weight 560.76 and chemical formula C29H36D8N8O3 for unambiguous identification.
- Supplied as a solid, white to yellow, convenient for storage and handling.
- Recommended storage: powder -20°C for long-term; in solvent -80°C for extended stability.
- Suitable for ADME, pharmacokinetic, and method validation studies.
Sigma Aldrich Fine Chemicals Biosciences Iodomethane-d3 >=99.5 atom % D, >=99% (CP), contains copper as stabilizer | 865-50-9 | MFCD00001074 | 50G
Iodomethane-d3 >=99.5 atom % D, >=99% (CP), contains copper as stabilizer | Purity: >=99% (CP) | Mol Wt: 144.96 | 865-50-9 | MFCD00001074 | 50G
Sigma Aldrich Fine Chemicals Biosciences Chloroform-d 99.8 atom % D, contains 0.03 % (v/v) TMS | 865-49-6 | MFCD00000827 | 10X0.6ML
Chloroform-d 99.8 atom % D, contains 0.03 % (v/v) TMS | Purity: >=99% (CP) | Mol Wt: 120.38 | 865-49-6 | MFCD00000827 | 10X0.6ML
Medchemexpress LLC L-Tryptophan-α,β,β,2,4,5,6,7-d8 | 1233395-93-1 | 212.27 | 50 MG
L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. This compound is suitable for use as a tracer or an internal standard in quantitative analysis techniques.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Dimethyl sulfoxide-D6 (D 99 9%) 0 03% v/v TMS serum bottle 25 g
Dimethyl sulfoxide-D6 (D 99 9%) 0 03% v/v TMS serum bottle 25 g
Medchemexpress LLC Zidovudine-d3 (azidothymidine-d3) | 30516-87-1 | 270.26 | 1 MG
Zidovudine-d3 is the deuterium labeled Zidovudine, a nucleoside reverse transcriptase inhibitor (NRTI) widely used to treat HIV infection.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes incorporated into drug molecules are used as tracers for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Ibuprofen-13C,d3 | 1261394-40-4 | C1213CH15D3O2 | 1 MG
Ibuprofen-13C,d3 is the 13C- and deuterium labeled Ibuprofen. Ibuprofen is an anti-inflammatory agent targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively. It serves as a valuable tool in research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Endoxifen-d5 | 1185244-45-4 | 97.5% | 378.52 | 1 MG
Endoxifen-d5 is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Zonisamide-d4 | 1020720-04-0 | 99.4% | 1 MG
Zonisamide-d4 is a deuterium-labeled version of Zonisamide, which is an inhibitor of the zinc enzyme carbonic anhydrase (CA). It demonstrates antiepileptic activity and is utilized in research for epilepsy, seizures, and Parkinson's disease. Deuterium labeling has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
Medchemexpress LLC Umbelliferone-d5 | 1215373-23-1 | 167.17 | 2.5 MG
Umbelliferone-d5 (7-Hydroxycoumarin-d5) is a deuterium-labeled coumarin derivative, a natural and orally active compound. It is a fluorescing agent and has shown diverse biological activities including anticancer, anti-inflammatory, and neuroprotective effects. This compound serves as a valuable tool for quantitative analysis in research.
- Deuterium-labeled for quantitative analysis
- Can be used as a tracer in drug development
- Acts as an internal standard for techniques like NMR, GC-MS, or LC-MS
- Exhibits anticancer effects by inducing cell cycle arrest and apoptosis
- Attenuates allergic airway inflammation
- Displays neuroprotective, anti-inflammatory, and antioxidant properties
Medchemexpress LLC 666-15 | 1433286-70-4 | MFCD30182343 | 99.8% | 620.52 g/mol | C33H31Cl2N3O5 | 1 MG
A potent, selective CREB inhibitor with an IC50 of 81 nM that has been reported to suppress tumor growth in breast cancer xenograft models. Supplied as a high-purity solid, the compound is provided for research use with defined storage and stability recommendations.
- Potent, selective CREB inhibition with IC50 = 81 nM.
- Demonstrated tumor growth suppression in breast cancer xenograft models.
- High purity, approximately 99.8%.
- Chemical formula C33H31Cl2N3O5; molecular weight 620.52 g/mol.
- White to off-white solid; store solid at 4°C and store solutions at -80°C for long-term stability.
- Supplied in milligram-scale quantities suitable for laboratory research.